Squalane (Fermentation-Derived)
Squalane is a highly stable, fully saturated hydrocarbon emollient produced via advanced yeast fermentation technology. Derived from renewable raw materials using a genetically engineered Saccharomyces cerevisiae strain with enhanced squalene biosynthesis capability, the resulting squalane closely resembles the lipid components naturally present in human sebum.
Through a controlled bioprocess involving fermentation, purification, and hydrogenation, this fermentation-derived squalane achieves exceptional purity, oxidative stability, and skin compatibility. Its colorless, odorless, and non-greasy nature makes it a versatile lipid ingredient for modern skincare, haircare, and sensitive-skin formulations, particularly where long-term stability and consumer comfort are critical.
Why Choose Fermentation-Derived Squalane?
Compared with traditional plant-extracted or animal-derived alternatives, fermentation-derived squalane offers greater consistency, sustainability, and formulation reliability.
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Biotechnology-based production ensures stable quality and batch-to-batch consistency
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Fully saturated molecular structure delivers superior resistance to oxidation
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Sebum-mimicking lipid profile enhances skin affinity and sensory performance
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Renewable, non-animal origin aligns with clean beauty and global sustainability trends
This makes fermentation-derived squalane a preferred emollient for premium and mass-market cosmetic brands alike.
Key Benefits
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Deep Moisturization & Barrier Support
Reinforces the skin’s lipid barrier and helps reduce transepidermal water loss (TEWL), supporting long-lasting hydration. -
Lightweight Skin Conditioning
Improves softness, smoothness, and elasticity without heaviness or greasy after-feel. -
Hair Conditioning & Anti-Static Performance
Enhances hair shine and manageability while minimizing static and flyaway effects. -
Outstanding Oxidative Stability
Maintains formulation integrity and extends product shelf life, even in complex systems. -
Skin-Friendly & Non-Comedogenic
Suitable for all skin types, including sensitive, baby care, and acne-prone formulations.
Typical Applications
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Facial and body creams, lotions, and serums
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Facial oils, cleansing oils, and balms
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Hair conditioners, serums, and scalp care products
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Sun care, lip care, and color cosmetics
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Baby care and sensitive-skin product lines
Its excellent sensory profile allows it to function as a primary emollient, co-emollient, or carrier oil, depending on formulation strategy.
Recommended Usage Level
| Application Type | Typical Dosage |
|---|---|
| Leave-on skincare | 1 – 20% |
| Hair care products | 0.5 – 10% |
| Cleansing formulations | 1 – 30% |
Actual dosage should be optimized based on formulation goals and sensory requirements.
Technical Information
INCI Name: Squalane
Source: Fermentation-derived (yeast-based)
Appearance: Colorless, clear oily liquid
Odor: Odorless
Typical Specifications
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Purity (Squalane): ≥ 98.0% (Typical: 99.7%)
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Relative Density (20°C): 0.810 – 0.820
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Refractive Index (20°C): 1.450 – 1.460
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Acid Value: ≤ 0.5 mg KOH/g
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Iodine Value: ≤ 4 g I₂/100 g
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Oxidative Stability: Highly resistant to oxidation
Microbial and heavy metal levels comply with cosmetic-grade regulatory requirements.
Formulation Notes
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Oil-soluble; easily incorporated into the oil phase
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Compatible with esters, vegetable oils, silicones, and common emulsifier systems
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Stable across a wide pH and temperature range
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Suitable for cold and hot process formulations
Its formulation flexibility makes it suitable for both simple emulsions and complex multi-phase systems.
FAQ
Is fermentation-derived squalane suitable for sensitive skin?
Yes. Its high purity, non-irritating profile, and similarity to natural skin lipids make it ideal for sensitive and baby care products.
How does fermentation-derived squalane differ from plant-based squalane?
Fermentation-derived squalane offers superior batch consistency, sustainability, and oxidative stability compared to many plant-derived sources.
Can it replace traditional emollients or oils?
Yes. It can be used as a partial or complete replacement for traditional oils, depending on formulation objectives.
Supply & Documentation
We provide cosmetic-grade squalane with stable supply and consistent quality for global markets.
Available documentation includes:
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Technical Data Sheet (TDS)
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Safety Data Sheet (SDS)
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Certificate of Analysis (COA)
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Formulation support upon request
Contact us to request samples, specifications, or pricing information.
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