Pyridoxine Tripalmitate CAS 4372-46-7

The Oil-Soluble, High-Stability Vitamin B6 Ester

Pyridoxine Tripalmitate is an oil-soluble, esterified derivative of Vitamin B6 (Pyridoxine), synthesized by combining three molecules of palmitic acid with a pyridoxine core. This molecular design transforms the typically water-soluble vitamin into a lipid-compatible, highly stable active ingredient, perfectly suited for integration into oil-phase cosmetic formulations. With a purity of ≥99% and presented as a fine white powder, it delivers the skin-conditioning and hair-manageability benefits of Vitamin B6 directly to lipid-rich structures of the skin and hair.

Why Choose Pyridoxine Tripalmitate?

For formulators seeking to enhance the conditioning and soothing efficacy of oil-based or emulsion systems, Pyridoxine Tripalmitate offers a scientifically advanced solution. Its exceptional lipid affinity and inherent stability overcome the limitations of pure Vitamin B6, ensuring long shelf life and potent activity in final products. It enables brands to add proven vitamin-based skincare and haircare benefits to a wider range of formulations—from rich creams and serums to lipsticks and sun care—without compromising stability or aesthetic elegance.

Key Benefits

• Enhanced Skin Conditioning & Comfort: Penetrates the lipid matrix of the skin to help improve smoothness, reduce the appearance of dryness and roughness, and support overall skin comfort.

• Soothing & Anti-Irritation Support: Contributes to a calming effect on the skin, helping to soothe the appearance of irritation and support skin barrier well-being.

• Superior Hair Manageability: Functions as an effective anti-static agent and combing aid in haircare, reducing flyaways, tangling, and improving overall combability for smoother, more manageable hair.

• High Stability & Oil Solubility: As a palmitate ester, it offers outstanding oxidative stability and seamless integration into the oil phase of formulations, preventing degradation and ensuring consistent performance.

• Versatile & Multifunctional: Serves as a dual-purpose active for both skincare (conditioning, soothing) and haircare (anti-static, manageability) applications, maximizing ingredient utility.

Typical Applications

Pyridoxine Tripalmitate is ideally incorporated into a variety of oil-phase or emulsion-based personal care products:

• Skincare: Nourishing creams, facial oils, anti-aging serums, soothing balms, and facial masks.

• Color Cosmetics: Lipsticks, lip balms, and other pigmented products where conditioning is desired.

• Sun Care: Sunscreen oils, after-sun soothing lotions, and protective balms.

• Hair Care: Hair oils, serums, conditioning treatments, and leave-in creams to combat static and improve manageability.

• Essential Oil Blends & Carrier Oil Formulations.

Recommended Usage Level

• Effective Concentration Range: 0.01% – 0.09%

• Note: This low dosage range is typically sufficient to deliver noticeable conditioning and manageability benefits. The exact optimal percentage should be determined based on the final product type and desired performance intensity.

Technical Information

• INCI Name: Pyridoxine Tripalmitate

• CAS Number: 4372-46-7

• Appearance: White to off-white crystalline powder

• Purity: ≥ 99%

• Solubility: Oil-soluble

• Function: Skin Conditioning Agent, Antistatic Agent, Hair Conditioning Agent

• Storage: Store in a cool, dry place in a tightly sealed container, protected from light and moisture.

• Shelf Life: 36 months under recommended storage conditions.

FAQ

1. What is the primary advantage over pure Pyridoxine (Vitamin B6)?
The key advantage is oil solubility and stability. Pure Vitamin B6 is water-soluble and can be less stable. Esterification with palmitic acid allows Pyridoxine Tripalmitate to be incorporated into the oil phase of formulations, offering superior compatibility with lipids, enhanced skin and hair penetration, and significantly improved long-term stability against oxidation and degradation.

2. Is it suitable for sensitive skin formulations?
Yes. Its role as a skin conditioner and soother, combined with its high purity (≥99%) and stability, makes it an excellent candidate for formulations designed for sensitive or compromised skin barriers. It helps improve skin comfort and reduce the appearance of irritation.

3. Can it be used in anhydrous (water-free) formulations?
Absolutely. Its oil-soluble nature makes it perfectly suited for anhydrous systems such as facial oils, oil-based serums, lip balms, and hair oils, where it can exert its conditioning benefits effectively.

4. How does it function as an antistatic agent in hair care?
It helps to neutralize electrostatic charges on the hair surface that cause static and flyaways. By improving the conductive properties of the hair and providing light conditioning, it makes hair smoother, easier to comb, and less prone to frizz and tangling.

5. Are there any specific formulation temperature restrictions?
It is stable under typical cosmetic processing temperatures. It is recommended to add it to the oil phase during heating, ensuring it is fully dissolved and homogenized before emulsification (if applicable).

Supply & Documentation

We ensure a reliable supply chain of high-purity Pyridoxine Tripalmitate (≥99%) to meet the production needs of cosmetic manufacturers and global distributors.

Available Documentation & Support:

• Detailed Technical Data Sheet (TDS)

• Material Safety Data Sheet (SDS)

• Certificate of Analysis (COA) for each batch

• Formulation Guidelines and Application Notes

• Regulatory Support Information

Customized Services:

• Bulk quantity supply with competitive tiered pricing

• Flexible packaging options

• Regulatory and compliance consultation for target markets

• Sample provision for R&D evaluation and testing

 Contact us to request samples, technical documents, or pricing information.

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