L-Carnosine is a naturally occurring dipeptide composed of β-alanine and L-histidine, widely present in living organisms. In cosmetic applications, it is valued for its dual antioxidant and anti-glycation activities, helping to protect skin cells from oxidative stress while slowing glycation-induced aging processes.
Unlike single-pathway antioxidants, L-Carnosine addresses both free radical damage and AGEs (advanced glycation end-products) formation, which are key contributors to skin stiffness, loss of elasticity, and premature aging. This multifunctional mechanism makes L-Carnosine an effective and science-backed active for advanced anti-aging and protective skincare formulations.
Why Choose L-Carnosine?
Dual Anti-Aging Mechanism: Oxidation + Glycation
L-Carnosine simultaneously neutralizes reactive oxygen species and inhibits protein glycation, targeting two major biological pathways of skin aging.
Cellular Protection at the Source
By protecting skin cells from oxidative and carbonyl stress, L-Carnosine supports long-term cellular resilience and skin barrier integrity.
Broad Formulation Compatibility
Water-soluble and stable across common cosmetic pH ranges, making it easy to integrate into diverse formulation systems.
Globally Accepted Cosmetic Active
Widely used in international cosmetic markets and suitable for export-oriented formulations.
Key Benefits
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Protects skin cells from oxidative stress caused by UV and environmental pollution
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Inhibits AGE formation to preserve skin elasticity and firmness
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Helps reduce visible signs of aging such as fine lines and uneven texture
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Supports skin barrier function and overall skin vitality
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Enhances long-term skin resilience in daily skincare routines
Typical Applications
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Anti-aging serums, creams, and lotions
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Brightening and revitalizing treatments
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Protective day creams and anti-pollution formulations
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Eye care products and neck creams
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Preventive skincare for early aging concerns
Recommended Usage Level
Typical dosage: 0.1% – 2.0%
The optimal usage level depends on formulation type, target claims, and desired efficacy. Compatibility testing is recommended for high-load systems.
Technical Information
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INCI Name: Carnosine
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CAS No.: 305-84-0
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Chemical Type: Dipeptide
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Solubility: Water soluble; slightly soluble in ethanol
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Recommended pH Range: 4.0 – 8.0
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Processing Note: Add during the cooling phase below 50 °C to maintain activity
Typical Specifications
| Parameter | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity (HPLC) | ≥ 99.0% |
| Loss on Drying | ≤ 0.5% |
| Heavy Metals (Pb) | ≤ 10 ppm |
| Microbial Limits | ≤ 1000 CFU/g |
| Yeast & Mold | ≤ 100 CFU/g |
| Pathogens | Not detected |
FAQ
Is L-Carnosine suitable for sensitive skin formulations?
Yes. L-Carnosine is generally well tolerated and suitable for daily-use skincare, including sensitive skin products.
Can L-Carnosine be combined with other antioxidants?
Yes. It works synergistically with vitamins, polyphenols, and other antioxidants to enhance overall formulation efficacy.
Is L-Carnosine suitable for long-term cosmetic use?
Yes. It is designed for preventive and long-term anti-aging skincare applications.
Supply & Documentation
Stable global supply and technical support are available. The following documents can be provided upon request:
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TDS
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SDS
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COA
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Regulatory support documentation
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Formulation guidance
Contact us to request samples, technical documents, or pricing information.
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