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Ascorbyl Glucoside CAS 129499-78-1

Ascorbyl Glucoside (AA2G,VCG)
Stable & Effective Vitamin C Derivative for Modern Skincare

Ascorbyl Glucoside (AA2G) is a gold-standard, enzymatically-activated Vitamin C derivative designed for superior stability and proven skin-brightening performance.

It delivers the antioxidant and collagen-boosting benefits of pure Vitamin C without the instability and irritation, making it ideal for effective, gentle formulations.

Key Highlights
1 Clinically Proven Whitening: Reduces melanin synthesis and lightens existing pigmentation.
2 Exceptionally Stable: Highly resistant to light, heat, and oxidation for long shelf life.
3 Gentle & Non-Irritating: Suitable for sensitive skin and long-term daily use.
4 Dual-Phase Soluble: Easily formulates into both oil-in-water and water-in-oil systems.

Recommended Dosage: 1-3%
Application Areas: Whitening Serums, Anti-Aging Creams, Sun Care, Toners

Trusted by cosmetic manufacturers and ingredient distributors worldwide.

Ascorbyl Glucoside (INCI: Ascorbyl Glucoside, CAS 129499-78-1), commonly known as AA2G, is a pioneering, glycosylated derivative of Vitamin C. Engineered for modern cosmetic science, it overcomes the notorious instability and formulation challenges of pure L-Ascorbic Acid. This ingredient delivers the full spectrum of Vitamin C benefits—including potent antioxidant activity, collagen synthesis stimulation, and effective melanin inhibition—through a stable, gentle, and skin-activated mechanism. As one of the most trusted and widely used skin-brightening agents globally, AA2G is the cornerstone ingredient for creating high-performance, visibly effective, and consumer-friendly skincare products.

Why Choose Ascorbyl Glucoside (AA2G)?

For formulators seeking the gold-standard in stable Vitamin C delivery, AA2G offers unparalleled advantages over its counterparts:

  • Superior Stability vs. Pure Vitamin C: Unlike L-Ascorbic Acid, which degrades rapidly upon exposure to light, air, and water, AA2G is highly stable. This ensures your formulations maintain their potency and appearance throughout their shelf life, reducing costly reformulations and customer returns.

  • Proven Efficacy with Gentle Delivery: AA2G is enzymatically hydrolyzed into active Vitamin C within the skin cells. This targeted release mechanism ensures high bioavailability where it’s needed most, while minimizing potential surface irritation associated with low-pH, pure Vitamin C formulas.

  • Formulation Versatility: Its excellent solubility in both aqueous and lipid phases provides exceptional formulation flexibility. You can incorporate AA2G into a wide range of products, from lightweight serums and clear gels to rich creams and sunscreens, without compromising stability or clarity.

  • Regulatory & Market Acceptance: As a published and approved skin-whitening agent by health authorities worldwide, AA2G offers a safe, scientifically-backed choice for global markets, simplifying regulatory compliance and strengthening product claims.

Key Benefits

  • Powerful Skin Brightening: Signantly inhibits tyrosinase activity, reduces melanin production, and helps expel existing pigmentation for a more even, radiant complexion.

  • Potent Antioxidant Protection: Neutralizes free radicals generated by UV exposure and pollution, helping to prevent photoaging and strengthen the skin’s defense system.

  • Anti-Aging & Firming: Stimulates collagen synthesis in fibroblasts, effectively improving the appearance of fine lines, wrinkles, and skin texture for a firmer, more youthful look.

  • Enhances Sun Protection: Acts as a synergistic booster in sunscreen formulations, providing additional protection against UV-induced cellular damage.

  • Excellent Skin Tolerance: Its non-irritating, gentle nature makes it suitable for all skin types, including sensitive skin, and allows for long-term daily use.

Typical Applications

AA2G is ideal for a broad spectrum of skincare products targeting radiance, anti-aging, and protection:

  • Whitening & Brightening Serums

  • Anti-Aging Creams, Lotions, and Night Treatments

  • Day Creams with Antioxidant Protection

  • Sunscreen and After-Sun Care Products

  • Toning Essences and Ampoules

  • Eye Creams for Dark Circle Reduction

  • Masks and Treatment Patches

Recommended Usage Level

  • Effective Range: 1% – 3% in the final product.

  • Standard Recommended Usage: 2% is typical for significant brightening and antioxidant effects.

  • For targeted, intensive treatments, levels up to 3% can be effectively used.

Technical Information

Parameter Description / Specification
INCI Name Ascorbyl Glucoside
CAS Number 129499-78-1
Appearance White to off-white (milky) crystalline powder
Solubility Soluble in water and oil phases (versatile)
Assay (Purity) ≥ 98.0% (Typical: 99.27%)
pH (1% Solution) 2.0 – 2.5
Storage Store in a cool, dry place in a tightly sealed container, protected from light and moisture.
Shelf Life 24 months from the date of manufacture under recommended storage conditions.

FAQ

Q1: How does AA2G compare to other Vitamin C derivatives like Ethyl Ascorbic Acid (EAC) or Tetrahexyldecyl Ascorbate (THD)?
A: The key difference is the activation mechanism. AA2G requires skin enzymes to convert it into active Vitamin C, ensuring targeted, slow-release efficacy with minimal irritation. EAC is more stable than pure Vitamin C but less stable than AA2G. THD is oil-soluble and penetrates deeply. AA2G is often preferred for its proven efficacy record, outstanding water-based formulation stability, and exceptional gentleness.

Q2: Is Ascorbyl Glucoside safe for sensitive skin?
A: Yes. Its gentle, enzyme-triggered release mechanism makes it one of the most skin-friendly Vitamin C derivatives available. It is widely used in products formulated for sensitive and reactive skin types.

Q3: Can AA2G be used alongside Niacinamide?
A: Yes, they are highly complementary. Niacinamide helps inhibit melanosome transfer, while AA2G targets melanin production at the source. Using them together can create a powerful, multi-pathway brightening and anti-aging formulation. No stability issues are reported when combined at cosmetic pH levels.

Q4: What is the optimal pH range for AA2G in formulations?
A: AA2G is stable across a wide pH range common in cosmetics (pH 3-8). Its conversion to active Vitamin C is driven by skin enzymes, not low pH, freeing you from the formulation constraints of L-Ascorbic Acid.

Supply & Documentation

We supply premium cosmetic-grade Ascorbyl Glucoside (AA2G) with guaranteed consistency and purity, backed by full transparency.

  • Packaging:

    • 1 kg/bag: Aluminum foil bag with an inner PE liner for optimal moisture and light protection.

    • 5 kg / 25 kg drum: Standard industry packaging for bulk production.

  • Full Documentation Support: We provide all necessary documents to ensure your seamless compliance and formulation success:

    • Certificate of Analysis (CoA) – Guaranteeing purity and specification compliance.

    • Safety Data Sheet (SDS)

    • Technical Data Sheet (TDS) with formulation guidelines.

    • Stability & Compatibility Data upon request.


Elevate your skincare line with the stability and efficacy of proven Vitamin C. Contact us today for samples, pricing, and technical partnership.

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Purity

≥99%

Molecular Formula

C₁₂H₁₈O₁₁

Molecular Weight

338.26 g/mol

Appearance

White to off-white powder

Usage

Cosmetic Raw Materials

Grade

Cosmetic Grade

Package

25 kg Drum or customized.

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