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O-Cymen-5-Ol CAS 3228-02-2

Broad-Spectrum Antibacterial Active for Acne-Prone & Sensitive Skin

A halogen-free, low-odor antimicrobial ingredient designed for modern cosmetic formulations.
O-Cymen-5-Ol effectively helps control acne-causing bacteria, soothe inflammation, and balance sebum production—while maintaining excellent skin tolerance and formulation stability.

Ideal for anti-acne, sensitive skin, oral care, and hygiene-focused cosmetic products.

Trusted by cosmetic manufacturers and ingredient distributors worldwide.

O-Cymen-5-Ol is a highly effective, broad-spectrum antibacterial cosmetic active widely used in acne-care, skin-soothing, and hygiene-focused formulations.
As a thymol isomer, it combines strong antimicrobial efficacy with excellent stability, extremely low odor, and high skin compatibility.

Unlike many traditional antibacterial agents, O-Cymen-5-Ol is halogen-free, mild, and well-tolerated, making it suitable for long-term use in skincare, oral care, and sensitive skin applications. Its ability to control microbial growth while maintaining skin comfort makes it a preferred functional ingredient in modern cosmetic formulations.


  • Why Choose O-Cymen-5-Ol?

    1 Broad-Spectrum Antibacterial Performance

    Effectively inhibits a wide range of bacteria associated with acne, inflammation, and skin imbalance.

    2  Mild & Non-Irritating

    Demonstrates low skin irritation, suitable for daily-use products and sensitive skin formulations.

    3 High Stability & Low Odor

    Chemically stable with minimal odor, allowing easy formulation without affecting sensory profile.

     4 Halogen-Free & High Acceptance

    Free from halogen elements, supporting higher regulatory acceptance in skin and oral care products.


    Key Benefits

    • Helps prevent and reduce acne formation

    • Soothes redness and inflammation associated with breakouts

    • Controls excess sebum while maintaining skin hydration

    • Supports pore-refining and skin-balancing effects

    • Provides UV absorption and antioxidant benefits as a multifunctional active


    Typical Applications

    • Anti-acne creams, gels, and lotions

    • Oily and acne-prone skincare products

    • Sensitive skin and calming formulations

    • Oral care products (e.g. toothpaste, mouthwash)

    • Personal hygiene and antimicrobial cosmetic products


    Recommended Usage Level

    • Suggested dosage: 0.03% – 0.10%
      The optimal level depends on formulation type, target efficacy, and regulatory requirements.


    Technical Information

    INCI Name: O-Cymen-5-Ol
    INCI (CN): 邻伞花烃-5-醇
    CAS No.: 3228-02-2

    Parameter Specification
    Appearance Colorless needle-like or granular crystals
    Odor Nearly odorless
    Melting Point 110 – 113°C
    Purity (HPLC) ≥ 98.0%
    Clarity (30% Ethanol Solution) Clear
    Arsenic (As) ≤ 2 ppm
    Heavy Metals (as Pb) ≤ 20 ppm
    Identification Maximum absorption at 279 nm ± 2 nm

    Formulation & Compatibility Notes

    • Suitable for a wide range of cosmetic systems

    • Compatible with common cosmetic ingredients

    • Maintains efficacy across typical cosmetic pH ranges

    • Ideal for multifunctional formulations combining antibacterial and soothing effects


    Supply & Documentation

    Huachem Ingredients Co., Ltd. supplies high-purity O-Cymen-5-Ol with stable quality and reliable global supply.
    Available documentation includes:

    • TDS / COA

    • SDS

    • Regulatory support files

    • Formulation guidance upon request

     For samples, specifications, or pricing, please contact our technical sales team.

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