Diaminopyrimidine Oxide is a hair growth active ingredient developed to address follicular degeneration and non-pathological hair loss. It is commonly used in anti-hair loss, hair regrowth, and hair density–enhancing personal care formulations.
By acting on dermal papilla cells and key follicular structures, Diaminopyrimidine Oxide improves the follicular microenvironment through multiple biological pathways. It supports the transition of hair follicles from the telogen phase to the anagen phase and helps prolong the active growth phase, contributing to visible improvements in hair density, strength, and overall hair vitality.
Why Choose Diaminopyrimidine Oxide?
Multi-Pathway Action on Hair Follicles
Rather than functioning as a simple stimulation agent, Diaminopyrimidine Oxide works on follicular structure, microcirculation, and cellular activity to comprehensively address hair loss concerns.
Designed to Target Follicular Fibrosis
Helps reduce abnormal collagen accumulation around hair follicles, softening fibrotic tissue and improving follicle elasticity, which is critical in preventing premature hair shedding.
Supports Prolonged Hair Growth Phase
Acts as a potassium channel opener, facilitating the shift from resting phase to growth phase and extending the duration of active hair growth.
Suitable for Global Formulations
Complies with cosmetic regulatory requirements in major markets including China, Europe, the United States, and Japan, making it suitable for export-oriented formulations.
Key Benefits
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Improves hair follicle activity and scalp vitality
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Helps reduce non-pathological hair loss
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Increases hair density and hair thickness
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Supports sustained hair growth with long-term use
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Suitable for scalp care and eyelash growth applications
Typical Applications
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Anti-hair loss shampoos
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Hair growth serums and scalp treatments
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Conditioners and scalp care products
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Functional styling products
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Seasonal hair loss repair formulations
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Eyelash growth care products
Recommended Usage Level
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Daily anti-hair loss / hair conditioning products: 0.5 – 1.5%
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Intensive hair growth or treatment-oriented products: 1.5 – 5.0%
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Eyelash care products: 0.5 – 1.5%
The optimal dosage should be determined based on formulation systems and target performance.
Technical Information
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INCI Name: Diaminopyrimidine Oxide
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CAS No.: 74638-76-9
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Molecular Formula: C₄H₆N₄O
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Molecular Weight: 126.12
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Appearance: White to off-white powder
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Purity (HPLC): ≥ 99.0%
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Solubility: Water soluble
FAQ
Is Diaminopyrimidine Oxide suitable for long-term use?
Yes. When used within recommended dosage levels, it is suitable for long-term cosmetic applications and daily scalp care products.
Can it be used in leave-on products?
Yes. Diaminopyrimidine Oxide is widely used in leave-on scalp treatments, hair growth serums, and eyelash care formulations.
Is it compatible with other hair growth actives?
Yes. It can be combined with common anti-hair loss and scalp conditioning ingredients, subject to formulation compatibility testing.
Supply & Documentation
Huachem supplies Diaminopyrimidine Oxide with stable quality and batch consistency, and provides complete technical documentation, including:
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Technical Data Sheet (TDS)
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Safety Data Sheet (SDS)
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Certificate of Analysis (COA)
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Regulatory support documentation
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Formulation and application support
Contact us to request samples, technical documents, or pricing information.








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