Product Profile
Pyrrolidinyl Diaminopyrimidine Oxide is a novel active ingredient for preventing hair loss and promoting hair regrowth. Unlike traditional hair growth agents such as minoxidil and finasteride, which are primarily limited to oral pharmaceutical use, this ingredient is designed for broad application in cosmetic and personal care rinse-off and leave-on formulations.
Mechanism of Action
Pyrrolidinyl Diaminopyrimidine Oxide is a potassium channel activator. Its multi-target mechanism supports hair follicle health and the hair growth cycle:
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Promotes Dermal Papilla Cell Proliferation: Acts as a potassium channel opener to stimulate the proliferation of key cells within the hair follicle.
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Stimulates Hair Follicle Regeneration: Encourages the reactivation and regeneration of hair follicles.
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Nourishes the Follicle: Helps improve microcirculation by promoting vasodilation, thereby increasing the supply of nutrients and oxygen to the hair root.
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Strengthens and Anchors Hair: Contributes to stronger, more resilient hair and helps reduce hair loss, resulting in increased hair density.
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Optimizes the Hair Cycle: Promotes a longer anagen (growth) phase and improves the anagen-to-telogen (A:T) ratio.
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Accelerates New Hair Growth: Acts on the deep structures of the hair root to stimulate the growth of new hair.
Efficacy
As a novel, oil-soluble active for preventing hair loss and promoting hair growth, Pyrrolidinyl Diaminopyrimidine Oxide helps restore hair follicle vitality, stimulate hair growth, prevent hair loss, and strengthen hair anchorage.
Applications
Suitable for a wide range of hair care products, including:
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Hair Gels
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Hair Oils
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Shampoos
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Conditioners
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Products targeting seasonal hair loss
Recommended Dosage
0.1% – 1.5%
Storage Conditions
Store in a cool place and keep tightly sealed.
Shelf Life
36 months under recommended storage conditions.








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